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NEWS and EVENTS

The Patent Cliff Threatens Billions of Global Pharmaceutical Sales

The patent cliff is real. During 2010 -2017 and during 2019-2024 approximately USD $150B and $198B respectively either have been and or are at risk of losing patent protection. Worldwide prescription drug sales are expected to grow at a CAGR of 6.9 percent to $842 billion during the 2019-2024 time period. This is triple the CAGR seen for 2010-2019 and is driven by an increase in FDA approvals for novel drugs and growth in the oncology therapies and orphan drugs markets.

Healthcare Economics (HCE) has developed extensive contacts with manufacturers, technology clusters, and academia to supply the needed link into each sector with its proven experience and globally developed extensive network. Therefore, the opportunity is immense for HCE to partner with firms to supplement their pipelines to ensure future success.

USA Biosimilar Approval and Launch Dates

Originator Trade Name Drug Name Innovator & Drug Name Approval & Launch Dates Innovator & Drug Name Approval & Launch Dates Innovator & Drug Name Approval & Launch Dates Innovator & Drug Name Approval & Launch Dates Innovator & Drug Name Approval & Launch Dates
Roche Herceptin Trastuzumab Mylan Ogivri
Dec 2017(A) Nov 2019(L)
Teva Herzuma
Dec 2018(A) Mar 2019(L)
Merck Ontruzant
Jan 2019(A) Apr 2020(L)
Pfizer Trazimera
Mar 2019(A) Feb 2020(L)
Amgen Kanjinti
Jun 2019(A) Jul 2019(L)
Roche Rituxan Rituximab Teva Truxima
Nov 2018(A) Nov 2019(L)
Pfizer Ruxience
Jul 2019(A) Jan 2020(L)
Amgen Riabni
Dec 2020(A) Jan 2021(L)
Pfizer Trazimera
Mar 2019(A) Feb 2020(L)
Amgen Kanjinti
Jun 2019(A) Jul 2019(L)
Roche Avastin Bevacizumab Amgen Mvasi
Sept 2017(A) Jul 2019(L)
Pfizer Zirabev
Jun 2019(A) Jan 2020(L)
J & J Remicade Infliximab Pfizer Ixifi
Dec 2014(A)
Pfizer Inflectra
Apr 2016(A) Nov 2016(L)
Merck Renflexis
Apr 2017(A) Jul 2018(L)
Amgen Avsola
Dec 2019(A) Jul 2020(L)
AbbVie Humira Adalimumab
Launch Delayed Until 2023
Amgen Amjevita
Sept 2016(A)
Boehringer Ingelheim Cyltezo
Aug 2017(A)
Merck Hyrimoz
Oct 2018
Merck Hadlima
Jul 2019
Amgen Enbrel Etanercept
On-going Litigation
Sandoz Erelzi
Aug 2016
Samsung Eticovo
Apr 2019
Amgen Epogen Epoetin Alfa Pfizer Retacrit
May 2018(A) Nov 2018(L)
Amgen Neupogen Filgrastim Sandoz Zarxio
Mar 2015(A) Sept 2015(L)
Pfizer Nivestym
Jul 2018(A) Oct 2018(L)
Amgen Neulasta Pegfilgrastim Mylan Fulphila
Jun 2018(A) Jul 2018(L)
Coherus Udenyca
Nov 2018(A) Jan 2019(L)
Sandoz Ziextenzo
Nov 2019(A) Dec 2019(L)
Pfizer Nyvepria
June 2020(A) Dec 2020(L)